A reduced level of DNA methylation has recently been described in both Zn-exposed and non-exposed offspring of Daphnia magna exposed to Zn. The hypothesis examined in this study is that DNA hypomethylation has an effect on gene transcription. A second hypothesis is that accumulative epigenetic effects can affect gene transcription in non-exposed offspring from parents [...]
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It has been previously demonstrated that vitellogenin (VTG) – a precursor egg yolk protein – is produced in male fish exposed to estrogenic compounds in wastewater treatment plant (WWTP) effluent. However, little attention has been given to examine whether any patterns of male VTG production exists across fish species on a global scale. We hypothesized [...] In previous studies we detected lower species richness and lower Hg sensitivity of the bacteria present in egested guts of Porcellio scaber (Crustacea, Isopoda) from chronically Hg polluted than from unpolluted environment. Basis for such results were further investigated by sequencing of 16S rRNA genes of mercury-resistant (Hgr) isolates and clone libraries. We observed up [...] Results: The probable daily intake (PDI) of MeHg for an adult population based on 60 kg body weight (bw was considerably higher in Wanshan than in the other three locations. With an average PDI of 0.096 µg/kg bw/day (range, 0.015–0.45 µg/kg bw/day), approximately 34% of the inhabitants in Wanshan exceeded the reference dose of 0.1 [...] Elevated concentrations of arsenic in drinking water are common worldwide, however, little is known about the presence of other potentially toxic elements. We analyzed 31 different elements in drinking water collected in San Antonio de los Cobres and five surrounding Andean villages in Argentina, and in urine of the inhabitants, using ICP-MS. Besides confirmation of [...] It has long been recognized that thyroid hormone (TH) is essential for normal brain development in both humans and animals, and there is growing evidence that environmental chemicals can disrupt the thyroid system. In the present work, we used a two-hybrid yeast assay to screen for agonistic or antagonistic thyroid receptor (TR) mediated effects in [...] Most of these chemicals are already out of use. The one commonly used substance, Lindane (and two of its production byproducts) is given an exemption on many of its current uses. The 9 new POPs |
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